Introduction: Talon cusp is an uncommon odontogenic anomaly which most Zico Vintage frequently affects maxillary permanent incisors.Its presence causes the problem in esthetics, prevention of caries, and occlusal accommodation for the patient and problems in the diagnosis and clinical management for the dentist.Case Report: This article reports a c
Smartcrystals for Efficient Dissolution of Poorly Water-Soluble Meloxicam
Nanocrystal is widely applied to improve the dissolution of poorly water-soluble drugs.We aimed to prepare meloxicam (MLX) Lip Treatment nanocrystals using the bead mill method, followed by high-pressure homogenization (HPH).Simple drying at room temperature (RD), vacuum-drying (VD), and freeze-drying (FD) using mannitol or trehalose as a cryoprote
Phosphorylation of the Archaeal Holliday Junction Resolvase Hjc Inhibits Its Catalytic Activity and Facilitates DNA Repair in Sulfolobus islandicus REY15A
Protein phosphorylation is one of the main protein post-translational modifications and regulates DNA repair in eukaryotes.Archaeal genomes encode eukaryotic-like DNA repair proteins and protein kinases (ePKs), and several proteins involved in homologous Storage Basket recombination repair (HRR) including Hjc, a conserved Holliday junction (HJ) res
A systematic review of translation and experimental studies on internal anal sphincter for fecal incontinence
The complexity in the molecular mechanism of the internal anal sphincter (IAS) limits preclinical or clinical outcomes of fecal incontinence (FI) treatment.So far, there are no systematic reviews of IAS translation and experimental studies that have been reported.This systematic review aims to provide a comprehensive understanding of IAS critical r